| Molecular Formula | C25H27N5O2
|
| Molar Mass | 429.51 |
| Density | 1.227±0.06 g/cm3(Predicted) |
| Melting Point | 173 - 174oC |
| Boling Point | 683.4±55.0 °C(Predicted) |
| Solubility | DMSO (Slightly), Methanol (Slightly) |
| Appearance | Solid |
| Color | White to Off-White |
| pKa | 5.29±0.10(Predicted) |
| Storage Condition | Hygroscopic, -20°C Freezer, Under inert atmosphere |
| Stability | Hygroscopic |
| In vitro study | Evobrutinib can inhibit the activity of BTK and prevent the activation of BCR signaling pathway. It can be metabolized by hydroxylation, hydrolysis, O-dealkylation, glucosidation and glutathione binding. |
